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Both systemic and local vascular impairments in vasodilation could exacerbate interglomerular pressure and injury (108)

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In addition, the prognostic assays described herein can be used to determine whether an agent (e.g., agonist, antagonist, peptidomimetic, polypeptide, peptide, nucleic acid, small molecule, or other drug candidate) can be administered to a subject to treat a disease or disorder associated with aberrant biomarker expression or activity

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