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doi:10.1136/jcp.42.6.624

New analytical techniques and current advancements in mass spectrometry allow for comprehensive data collection and a better understanding of the effects of different raw materials, starter cultures, fermentation temperature, and storage on the metabolite profile

216 In addition, PRMT4-catalyzed asymmetric dimethylarginine (ADMA) has been reported to bind to NOS as a ligand, leading to NOS dysfunction, resulting in decreased cerebral blood flow and aggravating AD, which can be reversed by inhibition of PRMT4

A careful clinical history especially one that includes tick exposure, co-infection risk, autonomic symptoms, and neurologic complaints can significantly affect the diagnostic process