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The investigation was done at two particular intervals, at 1 and 24 h

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J Pediatr Adolesc Gynecol 2009;22(4):257-263 Vercellini P, Fedele L, Pietropaolo G, et al

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Selenium: Synergistic selenium is required for glutathione peroxidase activity

However, side effects and secondary drug resistance of these proteasome inhibitors limit their wide applications (Figure 1), and then discuss potential implication of copper complexes as new UPS inhibitors in cancer treatment