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As a result, electrons accumulate at coenzyme Q, promoting incomplete oxygen reduction and excessive superoxide generation, thereby intensifying mitochondrial oxidative stress [28, 79]

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It was reported that MV-mediated delivery of CFTR protein was significant in correction of the transepithelial Cl current in well-differentiated HAE from CF donors [88]

All secondary antibodies were purchased from Cell Signaling Technology (4408, 4409, 4412, 4413, Carlsbad, USA)

USE IN SPECIFIC POPULATIONS SYNTHROID should not be discontinued during pregnancy, and hypothyroidism diagnosed during pregnancy should be promptly treated

A phase 2/3 randomized clinical trial followed by an open-label extension to evaluate the effectiveness of elamipretide in Barth syndrome, a genetic disorder of mitochondrial cardiolipin metabolism