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The FDA states there is insufficient information to know whether emideltide/DSIP would cause harm if administered to humans and notes peptide-related concerns such as impurities and immunogenicity, meaning unwanted immune reactions [3]

Both can be fed as a sole diet or supplement

Gao J, Yao Y, Liu C, Xie X, Li D, Liu P

No different distribution was observed in other genes ( Table S1 )

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In line with these findings, our data demonstrated that berberine treatments (50 and 100 mg/kg) markedly reversed the HFD-induced downregulation of lzm, hep, c3 , and igm , suggesting that berberine exerted a positive effect on the immune function in the liver of tilapia