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doi: 10.1007/s00421-018-3886-z 49 WangYLiuY

Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase

10.1038/nrmicro2070 Nat

GSH can also be oxidized to its disulfide form (GSSG) by reactive oxygen species (ROS) and other electrophiles, which can be reduced back to GSH by GR using NADPH as a reducing agent

Our findings also show sex-specific redox signatures in ME/CFS patients, such as elevated total ROS levels in women versus men, suggesting that the pathophysiology for ME/CFS and LC are distinct between genders