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References 1 Association American Diabetes

Cancers 12 , 951 (2020)

Phenolic compounds are the main active chemicals of green tea, comprising epigallo-catechin-3- gallate (EGCG), epicatechin-3-gallate (ECG), epigallocatechin (EGC), and epicatechin (EC), by reduction of IL-1, INF, TNF-, and iNOS, carry out an antioxidant, and anti-inflammatory activities ( The EGCG administration to EAE mice decreases brain inflammation and neuronal damage reducing the inflammatory infiltration, proliferation, and differentiation of auto-reactive T-cells in the CNS ( Also, the plasma levels of soluble intercellular adhesion molecule-1 (ICAM-1) and CD4 + T-cells expressing C-C chemokine receptor 6 (CCR6) are reduced in EAE mice treated with EGCG (Wang et al., 2012

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Grace CS, Mikkola HKA, Dou DR, Calvanese V, Ronn RE, Purton LE., "Protagonist or antagonist