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That led us to wonder whether a compound with strong antioxidant capacity might protect HGF, either by preventing nitration or by compensating for the functional loss it causes. The team turned to two sulfur-based compounds known for strong antioxidant activity: glutathione trisulfide (GSSSG) and lipoic acid trisulfide (LASSS)

The kynurenine pathway: A primary resistance mechanism in patients with glioblastoma

4 To prevent such damage, cells maintain redox homeostasis through an elaborate antioxidant defense system (Fig

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Modulation of gut microbiota by glycyrrhizic acid may contribute to its anti-NAFLD effect in rats fed a high-fat diet

One such mechanism involves the phosphorylation and activation of unc-51-like autophagy-activating kinase 1 (ULK1) by AMPK, which initiates a cascade that triggers autophagy