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Further, lycopene has been shown to elevate levels of IFN-, IFN-, interferon regulatory factor 1 (IRF1), IRF7, and C-X-C motif chemokine ligands 9 and 10 (CXCL9 and CXCL10), while reducing levels of IL-4, IL-10, DNA methyltransferase 3 alpha (DNMT3a), and methylation of IRF1 and IRF7 promoters, leading to a decrease in tumor volume in C57BL/6 mice after 40 mg/kg per day supplementation [59]

Collectively, these data suggest that AP exerts protective effects on airway smooth muscle by reducing hyperresponsiveness and inflammation through antioxidant and NO-mediated pathways

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Glutathione assay When cells experience oxidative stress the levels of glutathione decrease 43

This selectivity