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In addition, Caveolin-1 (Cav-1), a 21-kDa integral plasma membrane protein is a well-known negative regulator of eNOS activity in vascular endothelial cells 17,18,19,20,21,22

pylori -induced T-cell responses affect the small intestine and colon remains unclear

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10.1053/j.gastro.2010.09.010 80

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Unfortunately, this has been misinterpreted as "chemical improvement" and has formed the basis for the common habit of "chasing" or "treating" the creatine kinase level instead of monitoring muscle weakness, a practice that has led to prolonged use of unnecessary immunosuppressive drugs and erroneous assessment of their efficacy (36)