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The 10-year cost-effectiveness of lifestyle intervention or metformin for diabetes prevention: an intent-to-treat analysis of the DPP/DPPOS

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These symptoms could indicate a fractured bone or ruptured tendon

10.1002/jia2.25352 J

In addition, allosteric interaction with TrkB offers new opportunities, and a shift toward the crossed transmembrane domain of the TrkB receptor as a target for novel agonist pharmacophores should be considered in future development engaging the BDNF/TrkB signaling pathway (Pankiewicz et al., 2021)