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[DOI] [PMC free article] [PubMed] [Google Scholar] Souza JM, Peluffo G, Radi R

Hu M, An S

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KCs located in the interfollicular epidermis maintain the permeability barrier of the skin, crucial to sustain the hydration levels of the body

and T cells (e.g., CD4 + T-helper cells (Th) (major lineages including Th1, Th2, Th17, Treg) [233] and CD8 + lymphocytes (Tc) (major lineages include Tc1, Tc2, Tc9, Tc17, Tc22) [293, 521]), and regulatory B cell lymphocytes [382]

Nevertheless, these studies possess scientific significance in comprehending the fundamental pathophysiology and verifying innovative therapeutic and diagnostic methods, provided that a thorough assessment of the potential risks and benefits has been undertaken and the data is interpreted realistically