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Persistent inflammation further induces cytotoxic effects in healthy cells, causing DNA damage and activating autocrine and paracrine signalling loops that are influenced by epigenetic and microbial factors

Agerbirk N, Olsen CE

The Push Phase Goal The objective of the Push phase is to mobilize toxins from storage sites such as adipose tissue, the liver, and other tissues, making them available for elimination

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Free Radic Biol Med 63:5164 Schrammel A, Gorren AC, Schmidt K, Pfeiffer S, Mayer B (2003) S-nitrosation of glutathione by nitric oxide, peroxynitrite, and (*)NO/O(2)(*-)