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GSH is essential for immunomodulation of both innate and adaptive immune system functions, including T-lymphocyte proliferation, polymorphonuclear neutrophil phagocytosis, and dendritic cell functions, and is also important for fine-tuning the innate immune response to infection and for the first step of adaptive immunity involving antigen-presenting cell (macrophages, dendritic cells)-related antigen presentation (Morris et al., 2013

The skin distribution in dermal and epidermal layers of both compounds were also assessed

Funding This work was supported by the National Natural Science Foundation of China (82473906, 81971212), the Shenyang Young and Middle-aged Technological Innovation Talent Support Program (RC210268), and the Natural Science Foundation of Liaoning Province (2023-MS-153)

Biochemically, GABA levels were increased, leading to a slight reduction in glutamate levels and an improvement in the E/I balance

Rights and permissions About this article Cite this article Cirino, T.J., Alleyne, A.R., Duarte, V