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Also, Hcy may elevate ADMA levels by inducing ER stress and cell death, leading to increased proteolysis of proteins that contain methylarginine residues

M.et al (2018)

FEBS Lett 459(1):3338

Vitamin C also has its own tyrosinase-inhibiting properties, providing a double-layered approach to managing melanin

These findings indicate that the integration of the modified Zhengan Xifeng Decoction with cobamamide may offer superior therapeutic benefits in tinnitus associated with hyperactivity of the liver yang by targeting both symptomatic relief and underlying biological mechanisms