6.3 Critical assessment and challenges of SSP-targeted therapy 6.3.1 Target specificity and toxicity evaluation in normal tissues The SSP is not only aberrantly activated in tumor cells but also participates in fundamental metabolism in normal tissues, including the nervous system, immune cells and the liver
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doi: 10.52225/narra.v2i1.56
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B.JohannessonH.JohanssonH.HansonJ.EngstrmP.et al
At those organs, Gln is degraded and converted to glutamate, aspartate, CO 2 , pyruvate, lactate, alanine, and citrate, among other metabolites [10]
