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Second, the antioxidant effects observed in vitro or in animal models may not translate to meaningful clinical outcomes in humans due to complex metabolic interactions

Most mammalian mRNAs are conserved targets of microRNAs

116,605,606 Similarly, astrocytic reactivity seems to fade at the advanced stages of AD in human patients

Several large scale GWAS and meta-analyses for GSTM1 gene have identified the association between this gene and different lipid traits and many candidate gene association studies, especially LDL-C levels, ApoB, HDL, ApoA1, triglycerides, high total cholesterol level and Lp(a) [89, 94,95,96,97,98]

Therefore, future research must, while promoting translation, deeply dissect the dual roles of MR in different immune microenvironments to mitigate potential risks

Their proliferation, activation, and fusion directly determine repair efficiency