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Gonzalez, R., Lopez-Grueso, M

CNTNAP2 mutations may be associated with abnormal behaviors through alterations in synaptic neurotransmission, functional connectivity, and neuronal network activity

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The fact that HCQ targets mitochondria and decreases adenosine triphosphate (ATP) production and levels 8 , may account for its antiviral and toxic effects

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Quantification of protein levels by ELISA To accurately measure the hepatic concentrations of diverse proteins, encompassing the apoptotic regulators Bax and Bcl-2, as well as the principal inflammatory mediators TNF-, IL-6, NLRP3, and IL-1, the highly sensitive ELISA technique was utilized, employing specific commercial kits