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Heidelberg: Springer Science+Business Media, LLC

It has garnered attention for its potential to reduce inflammation, promote tissue repair, and support overall gut health

S.Gutirrez-de-TernH.et al (2016b)

While the needle puncture injury method provides reliable and consistent experimental disc degeneration models, findings from these studies need to be carefully interpreted and considered in a context dependent manner as the animal caudal spine differs in anatomy, mechanical load, and degrees of motion as compared to the human spine

This strategy effectively addresses the pharmacokinetic limitations of pGLP-2 while preserving its biological activity, offering a blueprint for the broader application of PEGylation in enhancing the stability and efficacy of therapeutic peptides vulnerable to enzymatic degradation

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