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Besides passive diffusion across bilayer membranes, uptake or efflux via membrane transporter molecules is of high significance for compound absorption, distribution and elimination ( metabolite was observed to be subjected to facilitated uptake via GLUT-1 transporters into erythrocytes and endothelial cells ( For Pycnogenol constituents and metabolites, interactions with some specific structures, such as matrix proteins ( in vitro

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Cut-off values have been established for these biomarkers, but although they may help physicians identify the most appropriate time to start treatment for kidney damage, no corresponding treatment exists (84)

K.XiS.SunT.et al (2023)

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