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In models of hind limb ischemia, it accelerated blood flow recovery and increased vessel density, highlighting its pro-angiogenic properties

People who get IV injections of ALA for diabetic nerve pain see improvement in about three weeks

These groups received intravenous administration of fluorescent drugs, each at a dosage of 2 mg/kg body weight

This one-two punch of more sugar in the blood and less sugar leaving the blood is why the spike can be so dramatic, even in people who have never had diabetes

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The pulsatile nature of this release is clinically significant: it mimics endogenous GH secretion rhythms, preserving downstream IGF-1 production, protein synthesis, and fat oxidation without the sustained GH elevation that can impair insulin sensitivity