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Study selection and data extraction were performed independently by two authors, with disagreements resolved by consensus or by consulting a third author

In addition to obesity, Covarrubias and colleagues found that during aging senescent cells significantly accumulate in visceral white adipose tissue and inflammatory cytokines found in the supernatant from senescent cells, which are induced macrophages to proliferate and to express CD38, as a T cell activation marker [73]

Further, scientists have explored DIP applications relating to its abilities to: 1/ influence hormones 2/ protect against stress 3/ reduce pain 4/ improve withdrawal management Another key benefit of DSIP is its neuroprotective effects

Multiscale Design of Cell-Free Biologically Active Architectural Structures

Information on covariates was collected by standardized questionnaire

Chen Z, Hu T, Zhu S, Mukaisho K, El-Rifai W, Peng DF