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In conclusion, endothelial cells and cardiomyocytes show some commonalities in mitophagy, especially in maintaining mitochondrial function and responding to cellular stress

The metabolite analysis demonstrated that Nrf2 strongly promotes purine nucleotide synthesis, resulting in the increased production of purine nucleotides

Weller, D., Andrus, A., Wiedmann, M

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Other natural interventions that may benefit patients with IBD include L-carnitine , glutamine , melatonin , vitamin K , and others

Acetate, propionate, and butyrate are essential microbial metabolites that in addition to host-centric functions in energy metabolism and immunological control, affect bacterial communities by modifying luminal pH, suppressing pathogenic overgrowth, and regulating quorum-sensing pathways 43