glutathione persister cells cancer

glutathione persister cells cancer Drug-tolerant are vulnerable to GPX4 inhibition Persistent Cancer Cells: The Deadly

Name: glutathione persister cells cancer Drug-tolerant are vulnerable to GPX4 inhibition Persistent Cancer Cells: The Deadly
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Persistent Cancer Cells: The Deadly Survivors: Cell Drug induced tolerant persisters in tumor: mechanism, vulnerability and perspective implication for clinical treatment Molecular Cancer Springer Nature Link Oncology Reports Glutathione peroxidase 4dependent glutathione highconsumption drives acquired platinum chemoresistance in lung cancerderived brain metastasis Liu 2021 Clinical and Translational Medicine Wiley Online Library Emerging Insights into Targeted Therapy Tolerant Persister Cells in Cancer Targeting of vulnerabilities of drug tolerant persisters identified through functional genetics delays tumor relapse ScienceDirect

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Weaver and Skouta, 2022)

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Inadequacies in antioxidant enzymes or their compromised metabolism will increase the concentration of reactive oxygen species (ROS) and, in essence, cause oxidative stress