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The answer to this mystery is that the group A carbohydrate-reactive B-1 B cells show a striking propensity to infiltrate the pancreas as Type 1 diabetes begins to develop in the mice

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Lacour B, Di Giulio S, Chanard J, Ciancioni C, Haguet M, Lebkiri B, Basile C, Drueke T, Assan R, Funck-Brentano JL (1980) "Carnitine improves lipid anomalies in haemodialysis patients." Lancet , 2, p

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