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Pharmacists should provide support and education around administration as summarised in Box 1

Long-term chronic dosing beyond 30 days has not been characterised in peer-reviewed human studies, and caution is appropriate outside the registered indications

By influencing these systems, PDA may contribute to improved recovery and a reduction in irritation or discomfort caused by inflammation

Most reported side effects are mild and temporary , with users occasionally experiencing: Injection site reactions : Redness, swelling, or localized discomfort Headaches or dizziness Gastrointestinal issues : Nausea or mild stomach discomfort These effects typically resolve on their own

Untested combinations: Novel or less-researched peptides lack even the limited safety information available for established compounds

Genetic factors could play a part in developing LSS