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Laboratory factors can also affect results, including assay interference (macro-B12) and variations in reference ranges between laboratories

The core chelation site relies on the imidazole ring of histidine and the side chain amino group of lysine to ensure the controlled release of copper ions

But payers prefer D50.0 when a cause exists

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When antibodies have waned below a titre of 40 to 80 (as measured by haemagglutination inhibition) they do not reliably protect against infection but can interfere with active immunisation (Fig

35 , 15481562.e1547 (2023)