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After synthesis, it enters the bloodstream and cerebrospinal fluid

Conjugation of TLR2 Pep to Maleimide Doped Oridonin-Liposome A cysteine (Cys) residue was synthetically appended to the C-terminal of the TLR2 targeting peptide, resulting in an amino acid sequence represented as His-Leu-Tyr-Val-Ser-Pro-Trp-Cys

Moreover, transport-related genes such as NPF5, NRT1, and NAET, which are involved in peptide, nitrate, and nicotinamide transport, were also significantly upregulated

10.1042/BCJ20190072 Biochem

Supported by these findings, many therapeutical strategies focusing on GCase have been introduced in recent years

Toft N, Birgens H, Abrahamsson J, Bernell P, Grikeviius L, Hallbk H, et al