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Downstream reaction that forms cysteine from cystathionine by cystathionase (CTH) has also been recently described to play a key role in adaptation mechanisms during cysteine-deprived induced stress in a wide variety of cancer cells lines (55)

Adler, V

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Loss of heterozygosity Loss of heterozygosity (LOH) is a common genomic alteration in GBM that drives tumor progression by disrupting tumor suppressor genes

We would also like to thank tProfessor Emeritus Shiro Kanegasaki of The University of Tokyo for his critical reading and Editage (www.editage.com) for English language editing