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In another study, cell cultures of patients with PEO/Kearns-Sayre syndrome grown in a medium containing KB, hence replacing glucose as the carbon source, showed reduced heteroplasmy mtDNA mutation levels (117)

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Once PCD is diagnosed, patients are advised to get further medical tests, checking the hearts health, blood sugar levels, and liver function, among others

These studies are the first to investigate age-dependent changes in the L-carnitine system as a surrogate for FAO within the cerebrovasculature from mice with different human APOE genotypes