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To this end, we constructed a LiCl-exposed pregnant mouse model by orally giving 0, 3.6, 20, 100, or 200 mg/kg/d LiCl (corresponding to 0, 1, 5.6, 28, and 56 -fold REED of Li) for continuous 13 days (Fig

Recently, the Bode group achieved a synthetic strategy for the formidable head-to-tail cyclized protein AS-48 via KAHA ligation 69

Drugs 65 , 23792404 (2005)

As expected, the chemically reactive metabolites were much more cytotoxic than their respective precursors and displayed comparable and steep dose-dependent decreases in cell viability ( Figure 2 )