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As awareness of skin cancer has grown, many individuals have shifted toward sunless tanning to achieve the cosmetic effects of a tan without the risks associated with ultraviolet (UV) exposure

The available human data from published literature and ongoing pregnancy registry studies on use of oxcarbazepine during pregnancy have not demonstrated an increased prevalence of major congenital malformations with first trimester exposure, though they acknowledge that the published studies do have limitations

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Diabetes 60 , 4755 (2011)

Yisireyili M, Shimizu H, Saito S, Enomoto A, Nishijima F, Niwa T (2013) Indoxyl sulfate promotes cardiac fibrosis with enhanced oxidative stress in hypertensive rats

Further, the review process was organized using the PICO (Participant, Intervention, Comparison, and Outcomes) framework, as described below: Participants: studies involving male patients or animals with reproductive system diseases or dysfunction