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Preclinical studies have laid a foundation for understanding its regulatory potential, but the translational gap exposed by GDNF/NRTN clinical trials underscores the need for humility in assessing its clinical value

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However, because the molecular response to mechanical stress is less well understood than the response to other abiotic stresses, this represents a significant research gap

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Increasing plasma fatty acids elevates F2-isoprostanes in humans: implications for the cardiovascular risk factor cluster