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It is a synthetic version of the naturally occurring hormone Melanotan II, which is responsible for the production of melanin in the body

The standardized mean differences clearly favored tirzepatide across all treatment groups

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Compared to the wild-type cell lines, UCP2-silenced Kras mutant cell lines have lower glutaminolysis, NADPH/NADP + , and glutathione/glutathione disulfide ratios and higher ROS levels

Studies on animal models (mainly mice and rats) indicate the involvement of this peptide in the processes of extracellular matrix (ECM) remodeling and angiogenesis

Nevertheless, building upon the optimized system and potentially incorporating methods like monitoring cell membrane depolarization, there is prospective potential to adapt the technology for rapid AST of slow-growing microorganisms, thereby expanding its application scope