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Both can be injected subcutaneously at the same anatomical site (abdomen, thigh) but as distinct injections administered sequentially

But many of the products have never been extensively studied in humans, raising concerns that they could cause allergic reactions, metabolic problems and other dangerous side effects

Perrone writes for the Associated Press.

Over the past 2 decades, several studies have highlighted a substantial increase in the risk of vitamin B12 deficiency in patients with T2D on metformin therapy

Specific cells in the stomach lining, called parietal cells, secrete two substances that are important to B12 absorption

That said, deficiency is rare and can only be confirmed through a lab test