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3,5 There are also some commonly prescribed medications that can deplete B12 levels

Acknowledgements We acknowledge the NIH Multi-Institute Cryo-EM Facility (MICEF), the NHLBI Biophysics core facility, Light microscopy core facility, X

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By mapping Chr21, the APP gene encodes the amyloid precursor protein and the EST2 gene encodes a transcription factor that further promotes the expression of APP , resulting in increased production of A oligomeric toxic peptides, which form the backbone of amyloid plaques (463)