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Because the liver affects so many systems, the signs of a "taxed" filter can be subtle: Persistent Fatigue: When the liver is busy managing a high toxic load, it can drain the body's overall energy resources

No effects were observed in Wistar rats exposed to a lower concentration, 5 days/week for 4 weeks, either as a "continuous" (6 h/day) exposure of 270 mg/m 3 , or as a time-weighted average of 255 mg/m 3 after the described intermittent low-high exposure

1. Prevents Fatigue

We deduced that these cells pre-existed in the mDA area and possibly expressed low levels or no TH in adulthood

[DOI] [PMC free article] [PubMed] [Google Scholar] Doctrow S.R., Huffman K., Marcus C.B., Musleh W., Bruce A., Baudry M., Malfroy B

2013 Jul;169 Suppl 2(0 2):1-8