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To explore the mechanism by which loss of GLP-1R caused impaired brain glucose metabolism, we examined the levels of cAMP in whole brain tissues

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This approach is especially useful for individuals with high toxic loads or chronic exposure to pollutants

However, if polymorphisms in the glucoronosyI transferases reduce the V max values to 50% of normal then the number of hepatocytes drops to about 75% of normal after 20 hours