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At the same time, Cu(I) is oxidized back to cupric species Cu(II)

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Recently, evidences from clinical studies such as NCT01811992 adenoviral vector-based combination (cytotoxic and immunotherapy) therapy for HGG showed no treatment release deaths indicating the safety of viral vectors for therapeutic applications [165]

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The activation of CASPASE-4 , due to promoter hypomethylation, enhanced the release of IL-1, aggravating neuroinflammation and accelerating A plaque formation (Daily et al., 2024)

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