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Correction of glutathione deficiency in lower respiratory tract of HIV seropositive individuals by glutathione aerosol treatment

Aspergillus can cause severe asthma when the mold colonizes the lung, forming a granulomatous disease

New basic and clinical research is clarifying the mechanistic relevance and therapeutic feasibility of multiple targets within the glutamate system for novel drug discovery, including NMDA and AMPA (-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) receptors, metabotropic glutamate receptors, and other key regulatory proteins such as glycine transporter 1 and excitatory amino acid transporters

Ohkama-Ohtsu N, Oikawa A, Zhao P et al (2008) A -glutamyl transpeptidase-independent pathway of glutathione catabolism to glutamate via 5-oxoproline in Arabidopsis

it is a state of global lowered pain threshold caused by abnormal brain processing of sensory stimuli