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treatment selection follows

The tryptophan 5-hydroxylase 1, crucial for the synthesis of serotonin (5-HT), and tyrosine hydroxylase, a rate-limiting enzyme in the production of dopamine, adrenaline, and noradrenaline, are both positively regulated by SCFAs (175, 176)

Dopaminergic therapies such as levodopa, dopamine agonists, and monoamine oxidase B (MAO-B) inhibitors provide meaningful relief, particularly during the early stages of the disease, but their efficacy wanes over time [5]

As a conclusion, ozone treatment seems to have a beneficial effect on RBCs

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Ewa, PK, Giulia, N, Florent, D, Damarys, L, Patrick, P, Yi, X, Kopetz, S , Jennifer, D, Lucie, P, Catherine, RM, Philippe, S, Patrick, TC, Shaynoor, D