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Baar et al, Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging

To investigate whether S-nitrosylation of MYCN at specific cysteine residues contributes to NO-mediated suppression of ER stress in NEPC, we generated site-directed mutations at Cys4, Cys186, and Cys464 (Supplementary Fig