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The exact cause of neuronal cell death in AD has not been fully established but could involve a number of apoptotic, necrotic, pyroptotic, ferropoptotitic and perhaps cuproptotic cell death (Mangalmurti and Lukens, 2022

Sequenced application (separate products at different times) is the more common research approach

When the MTHFR is not functioning at full capacity, thus causing a gene mutation, it increases the risk of developing autoimmunity

In: Nutrition and lifestyle in neurological autoimmune diseases

Kondo K, Hashimoto H, Kitanaka J, Sawada M, Suzumura A, Marunouchi T, et al

doi:10.7759/cureus.28307 [13] Freeman AM, Rai M, Morando DW