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The impaired mitochondrial fails to produced sufficient ATP in a short time to activate VGCC, leading to impaired release of insulin granular, 123 while the downregulation of PDX1 and MAFA results in reduced transcription of insulin

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Determination of isosbestic point At a concentration of 10 g/ml, all three drugs were run in UV spectrophotometer

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FDP has an oral bioavailability of approximately 15% in humans, primarily due to its poor water solubility and extensive first-pass metabolism in the liver and gut wall