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In glioblastoma, mitochondrial Nip3-like protein X (NIX), whose expression levels are increased by NRF2, promotes HIF elevation, resulting in the maintenance of glioblastoma stem cells 63

A score 7 predicted death, whereas a score 6 predicted survival with chelation therapy

J Mater Sci Nanotechnol

Its primary role is to maintain cellular function and structure

These data confirm that microfluidic control not only operationalizes the dynamic microenvironment described at the outset but also yields a more defined epidermal structure than static models

Although they are asymptomatic and referred to as silent, these mucus plugs are associated with worse functional, structural, and clinical disease measures, including reduced FEV 1 , worse exercise capacity, greater emphysema, thicker airway walls, and a higher likelihood of severe exacerbation [44]