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These include: Toxic exposures: mold, heavy metals, tick-borne illness, among others Hormonal contributors: hysterectomy before age 41, menopause, hypothyroidism, adrenal fatigue Head Injuries Insulin resistance and/or diabetes Chronic Insomnia and/or Sleep Apnea Nutrient deficiencies What Else Can I Expect

2009;297:C12001210

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The following guidelines represent standard approaches based on available research and community experience

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Additional restriction to immune access is conferred by physical barriers of structural ECM remodeling, whereby tumor-derived discoidin domain receptor 1 fragments realign collagen fibers, forming physical barriers that impede immune cell penetration (177)