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Graphical Abstract Similar content being viewed by others Introduction Malignant tumors are still a difficult problem to solve urgently

Chest 128 , 518524 (2005)

doi: 10.1002/2211-5463.12283 19 TadaMAoyamaMIshii-WatabeA

Thus, when the GDH gene is suppressed using an antisense approach, the AsA content in thale cress tissues exposed to high light irradiation decreases significantly (Gatzek et al., 2002), confirming so the role of the GDH enzyme for AsA biosynthesis in plants, as has been previously demonstrated the late 1990s by Smirnoffs research team (Wheeler et al., 1998)