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Minicircular DNA vectors, which lack bacterial backbone sequences, can more efficiently enhance transgene expression and reduce innate immune activation compared with plasmids

10.1016/j.jri.2016.03.001 62 HosseiniS.ShokriF.PourS

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During the progressive stage of cancer, intracellular GSH rates are upregulated to oppose the considerable ROS, thus protecting cancer cells from apoptosis induced by oxidative stress [27]