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Researchers study it for its role in innate immune defense, epithelial signaling, and host-pathogen interaction throughout the GI tract

doi: 10.1038/ncb3107, 119 RieraL.ObachM.Navarro-SabatA.DuranJ.PeralesJ

The mechanism of gastroprotection by melatonin or its precursor has been attributed to scavenging of free radicals and to its ability to attenuate lipid member peroxidation, neutrophil induced infiltration and cytotoxicity caused by mucosal irritants (52-57)