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A 2003 animal study using GHRP class peptides demonstrated that a single nocturnal pulse of GH secretagogue produced IGF-1 elevations comparable to twice-daily dosing in some species, though extrapolation to humans remains cautious

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Various studies have tried to identify biomarkers that could predict the development of PCC [24]

In 2002, it was shown that symptomatic, unstable plaques demonstrated increased uptake of the glucose analogue [18F]-fluorodeoxyglucose compared to asymptomatic plaques, whereas healthy carotid arteries did not show glucose uptake (Rudd et al., 2002)